Vagheggi Phytocosmetici / Nuon Medical - 75.25 Longevity Day Cream + Efficacy

This longevity-boosting formula is crafted with a Nuon Medical skin care device in the product’s cap, which enhances the product’s skin benefits. The formula is shaped around the longevity molecule NAD+ Activator, that delivers a rejuvenating effect of around 8.2 years. It stimulates regenerative processes, regulates energy production, and helps prevent inflammaging. The ingredient thus supports the skin in counteracting wrinkle formation, collagen loss, and the build-up of cellular waste. Derived from plant sprouts, this active boosts the production of NAMPT, addressing most of the 12 hallmarks of longevity. And lapacho bark extract helps protect DNA telomeres, contributing to delayed cellular aging and senescence. It strengthens the dermal-epidermal junction and stimulates the synthesis of collagen, elastin, and hyaluronic acid. This in turn helps reduce wrinkles and restores firmness and radiance. After application, the device – combining red light of 630 nm, microcurrent, heat, and vibration – is used for three minutes.

August 28, 2025

Pot 50 ml € 160,00 Refill 50 ml € 85,00

- Vagheggi rewrites the rules of cosmetics with 75.25, the line that ushers in a new era in skin longevity: an integrated system where product and technology become one. For the first time, a cosmetic product is created alongside its beauty device. Not separate. Not accessories. But designed contextually to work synergistically, right from the formulation stage. - The formula features innovative longevity active ingredients, including a NAD+ Activator and Lapacho bark extract, improving wrinkles, tone, and radiance. - The Efficacy Booster Device combines red light (630 nm), microcurrent, heat, and vibration for enhanced professional anti-ageing skincare results.

A scientific approach to skin longevity; it doesn't just fight aging, it works to reduce the biological age of skin tissue, specifically targeting the 12 hallmarks, alterations underlying aging identified by epigenetic and omics research. At the core, a new generation of targeted active ingredients for precision cosmetics. Benefits: - A high-performance cosmetic beauty routine with immediate results. A highly functional day cream with targeted pro-age action, it: 1. Increases skin firmness 2. Redefines the V-shape 3. Improves overall skin appearance for a younger-looking complexion 4. Counteracts wrinkles and skin sagging - Maximum cosmetic innovation. Ideal for beauty addicted who want to be the first to use this new type of beauty routine - Easy to use. An innovative cap transforms into a multifunctional beauty device that enhances the efficacy of the Longevity Day Cream. By combining red light at 630 nm, microcurrents, heat and vibration, it delivers targeted skin rejuvenation. - Speed of use The result is a smoother, firmer and more radiant-looking face in just 3 minutes. - A daily moment of wellbeing. Beyond performance, the product offers a sensorial escape to start the day positively.

1. Instrumental testing demonstrated an average wrinkle depth reduction of –14.8%, with peak values reaching –40%. 
2. In the self-assessment test, 100% of participants reported improvements in firmness, radiance and hydration, as well as a lifting and reshaping effect. The treatment was also rated as easy to use and sensorially pleasant. 
(*) Tests conducted on 20 subjects aged between 40 and 65 with visible skin wrinkling. For 14 days, Longevity Day Cream was applied twice daily and the 75.25 Efficacy Booster Device was used once daily for a total of 3 minutes. 
3. Patch test

The product comply EU Cosmetics Regulation, China’s NMPA and it is produced applying GMP certification The device is certified CE and approved in a lot of country in the world

NAD+ ACTIVATOR (LONGEVITY MOLECULE) The NAD+ Activator is an active ingredient that can deliver an average rejuvenating effect of -8.2 years on the skin’s biological age (*). It was specifically included in the 75.25 line to stimulate regenerative processes, regulate energy production, and help prevent “inflammaging.” In doing so, it supports the skin in counteracting wrinkle formation, collagen loss, and the buildup of cellular waste. Derived from plant sprouts sustainably grown in bioreactors, this active boosts the production of NAMPT, addressing most of the 12 hallmarks of longevity. Overall, it acts as a true energy and renewal booster for the skin, with a deep anti-wrinkle, re-densifying, and reshaping effect. LAPACHO EXTRACT (YOUTH ACTIVATOR) Lapacho bark extract (Tabebuia impetiginosa bark extract) is a targeted active that helps protect DNA telomeres, contributing to delayed cellular ageing and senescence. It strengthens the dermal–epidermal junction and stimulates the synthesis of collagen, elastin, and hyaluronic acid. This helps reduce wrinkles and restores firmness and radiance. The Lapacho bark is sourced from a 100% female-owned family business in Paraguay, working with small producers and growers while promoting women’s empowerment. The bark comes from trees included in a reforestation program, ensuring an approach that respects the environment and natural resources. INCI: Aqua/Water/Eau, Caprylic/Capric Triglyceride, Propanediol, C9-12 Alkane, Behenyl Alcohol, Cetyl Palmitate, Canola Oil/Huile De Colza, C10-18 Triglycerides, Cetyl Phosphate, Coco-Caprylate/Caprate, Pentaerythrityl Tetraisostearate, Butyrospermum Parkii (Shea) Butter, Arginine, Squalane, Tabebuia Impetiginosa Bark Extract, Helianthus Annuus (Sunflower) Sprout Extract, Sodium Carboxymethyl Betaglucan, Sodium Hyaluronate, Brassica Campestris (Rapeseed) Seed Oil, Maltodextrin, Parfum (Fragrance), Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Ethylhexylglycerin, Tocopheryl Acetate, Xanthan Gum, Isohexadecane, 1,2-Hexanediol, Caprylyl Glycol, Tridecane, Polysorbate 80, Sodium Gluconate, Hexyl Cinnamal, Sorbitan Oleate, Polyglyceryl-3 Diisostearate, Citrus Limon (Lemon) Peel Oil, Limonene, Vanillin, Pinene.

- Sustainable Packaging: o 'Lightweight' glass jars and bottles to reduce environmental impact, monomaterial airless for proper disposal, refill systems in stand-up pouches with a screw cap to prevent loss. o Cases made with natural papers, FSC certified, of pure E.C.F cellulose, completely biodegradable and recyclable.

Vagheggi, a renowned company in the skincare and cosmetics sector, is proud of its commitment to quality, sustainability, and ethical practices. These certifications highlight Vagheggi’s dedication to meeting the highest standards in product manufacturing and environmental management. ISO 22716 Certification for Good Manufacturing Practices: This certification demonstrates Vagheggi’s compliance with strict guidelines for the production, control, storage, and shipment of cosmetic products. It ensures that the company maintains high levels of quality and consistency throughout its manufacturing processes. The product is tested for safety and efficacy.

- Use the product every morning for a high performance skincare beauty routine and promote a sensational feeling of wellbeing. - Clean the skin and gently pat dry. Apply a thin layer of Vagheggi 75.25 cream. - Activate the device (see the specific quick guide) and use it on the cream. Move the device slowly and gently over the treatment area for 3 minutes. The device will automatically turn off after 3 minutes. The cycle can be repeated if desired, up to 12 minutes total. The result is a smoother, firmer and more radiant-looking face.

All over the world, Beauty salon, SPA and e-commerce.

Website: https://www.vagheggi.com/en Instagram: https://www.instagram.com/vagheggiofficial/ Corporate IG: https://www.instagram.com/vagheggi_corporate/ Facebook: https://www.facebook.com/VagheggiPhytocosmesi Shop: https://shop.vagheggi.com/75-25vagheggi When formula and device are born together, skincare becomes an experience of perfection.